Progranulin in frontotemporal lobar degeneration and neuroinflammation
Abstract Progranulin (PGRN) is a pleiotropic protein that has gained the attention of the neuroscience community with recent discoveries of mutations in Figure Skating - Clothing - Adult Activewear the gene for PGRN that cause frontotemporal lobar degeneration (FTLD).Pathogenic mutations in PGRN result in null alleles, and the disease is likely the